Particular Sciences product catalogue - Nov 2015

P articular Sciences was formed almost 25 years ago to provide specialist support in

material characterisation technologies for chemists, biologists, researchers and

industrial clients in Ireland, North and South.

“ T his is a niche business, filling what was previously a gap in the scientific infrastructure , one that was

limiting the adoption of new analytical technologies.

W e started in business with one product range, a compact customer base, one employee and grew with

the market. Ireland is still attracting industrial multinationals and the scientific infrastructure is maturing to support these.

W e supply instruments and service to over 200 companies across pharmaceutical, chemical, minerals,

food, pigment sectors and increasingly into research areas where nanotechnology and biotechnology applications are at the top of the list.

P articular Sciences represents a select group of specialist companies like Malvern, Micromeritics and Biolin Scientific who are clear leaders in their fields. Some may not realise the extent our product range, so this brochure gives a view of our specialist instruments and equipment. There are also some new models from old friends and novel technologies looking for applications.

P articular Sciences hold true to their original concept as we concentrate on material sciences. We strive

to offer the level of support as our principals provide so that you can maximise the use of the technologies you purchase. “

Sean P. Quilty

Particular Sciences Ltd

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Particular Sciences Ltd

The companies we represent

Biolin Scientific

4~7

Micromeritics

17 ~ 23

Bionavis

7

NanoSight

11

Formulaction

8

Optical Activity

23

Freeman Technology

9

Phenom World

24

Index Instruments

9

PostNova Analytical

24

Lamy Rheology

10

Relequa

5

Malvern Instruments

4, 10 ~ 16

Sequoia Scientific

25

Microfluidics

16

Surface Measurement Systems

26 ~ 27

The technologies we support

Particle Sizing technologies

Surfaces & related:

Molecular binding & related:

Dynamic Light Scattering

12

BET SSA

17

QCM-D

6

Laser Diffraction & NTA

11

Gas Physisorption

18

MP-SPR

7

Velocimetry

15

Chemisorption

19

Stability & bulk properties

Vision

13

Hg Porosimetry

20

Powder Flow 9

Static Light Scattering

12

Micro Porosimetry

19

Rheology

14

GPC & SEC, SEC MALS

13

DVS

26

Micro-Rheology

8, 12

Process sizing

16

ERH moisture

25

Emulsion stability

8

Sprays

15

IGC and SEA

27

Optical

Particle size reduction

16

Tensiometry

4~5

Polarimetry

23

Particle Counting

23

LB troughs

6~7

Refractive Index

9

Asymmetric FFF

24

Pycnometry

21

Microscopy

13, 24

Resonant Mass measure

4

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Archimedes

Sub-micron particle metrology

Archimedes is a new, innovative instrument that uses the technique of resonant mass measurement to

detect and accurately count particles in the size range 50nm - 5µm, and reliably measure their buoyant

mass, dry mass and size. Particularly useful for

the characterization of protein aggregates in

formulation or buffer, Archimedes is also able to

distinguish between proteinaceous material and

contaminants such as silicone oil by means of

comparing their relative resonant frequencies

and buoyant masses as seen in the slide below.

Biolin:

Attension

Tensiometry

Attension is the Biolin Scientific brand of tensiometers for all types

of surface measurements. Tensiometry is the measurement of the

surface tension of liquids, and can be performed optically on a pen-

dant or sessile drop as with bench top Theta tensiometers shown in

the photo or on a force system such as the Sigma series shown on

next page.

All Theta models offer Contact Angle measurements on surfaces to

assess the wetting or wettability; where a  < 90 degrees indicates

good wetting and >90 is poor wet-

ting; also adsorption studies and

techniques from static and dynamic

contact angles to surface / interfacial

tensions, drop volume and surface

free energy.

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The “OneAttension” software enables superior analysis of drop shapes

using the Young-Laplace equation which fits the entire drop profile and

is the reference method. OneAttension is all-inclusive with no separate

software modules. It features an intuitive user interface, live analysis,

configurable user groups and accounts and a pre-set liquid database.

Attention 3D Topography module on Theta measures the roughness of

surfaces on coatings, materials and medical implants as well as contact angle, at the same location.

Sigma Force tensiometers, like shown below, work with mass

balances to measure the force of meniscus between a solid

like the Wilhelmy Plate and a liquid. Or have push and pull

modes with Du Nouy rings (shown in diagrams) or with a

Platinum Rod.

Force tensiometry used in Sigma has become the method of choice for

many industrial standards. It is also the most widely used technique for

measuring critical micelle concentration of surfactants. In addition, it is

the only method to determine the absorption and contact angle of a

packed powder or of fibre beds using the Washburn method. The wetting

of textiles and individual fibres can also be studied with Sigma force

tensiometers.

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Biolin:

Qsense

Quartz Crystal Microbalance with Dissipation

Q-Sense develops research instruments based on their patented Quartz

Crystal Microbalance with Dissipation monitoring (QCM-D) technology. These

products are suitable for studying molecular interactions and surface science,

mass and structural changes at the nanoscale level.

The QCM method is based on a vibrating quartz crystal sensor (acoustic

resonator). Measurements are made of changes in vibration frequency in

response to reactions that occur on the sensor surface.

QCM-D uniquely monitors the frequency and energy dissipation response of

the freely oscillating sensor. QCM-D enables real-time, label free

measurements of molecular adsorption and/or

interactions on various surfaces. In addition to

adsorbed mass (ng/cm2 sensitivity), measured as

changes in frequency of the quartz crystal, the

dissipation parameter (D) provides novel insights

regarding structural (viscoelastic) properties of

adsorbed layers.

Qsense have just launched a new high end automatic

system, the Omega auto to extend the range from

stand alone E1 to a four sensor E4 and now the

multipurpose Omega with 8 sensors in 4 pairs for kinetics and unattended workload.

Biolin:

KSV NIMA

Langmuir troughs

KSV NIMA produce high quality Langmuir and Langmuir

Blodgett troughs for monolayer production and

experimentation.

These come in

various sizes and

budget levels, with

accessories and extra

facilities to suit any requirement you may have. KSV and NIMA

were well regarded before joining forces and now can be said

to make the best thought-out, best engineered and most

reliable LB troughs in the world.

And for all that, it is not that expensive to own the best in Langmuir troughs.

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Newly released is the KSV NIMA Ribbon Barrier Trough for studying lung surfactants at high compression

without leakage. It can also be used to deposit monolayers at high

packing densities onto solid samples.

Deposition enables further characterisa-

tion of your film with complementary

techniques such as QCM-D and AFM.

KSV NIMA also produce the Interfacial

Shear Rheometer, a wide range of Dip Coaters and the FTIR based PM-IRRAS system for advanced char-

acterisation.

A Brewster Angle Microscope (BAM) option enables the visualization of Langmuir monolayers or adsorb-

ate films at the air-water interface. In conjunction with a Langmuir Trough, it enables the study of Mon-

olayer/film behaviours like phase changes, phase separation, domain size, shape and packing. When

combined with a KSV NIMA L or LB Trough, observation can be performed during compression/expansion

at known surface pressures.

Bionavis

SPR Navi Surface Plasma Resonance

”Bionavis strive to develop Surface Plasmon Resonance (SPR) technology beyond today’s understanding. We manufacture SPR instruments with superior features and performance.” The new 6 sample SPR Navi™ 210A has been developed in collaboration with Dr. Janusz Sadowski who was the main driver in the re-

search of SPR technique at VTT for over 20 years, and Dr. Ulf Jönsson, the founder and former CEO of

Biacore, the company that pioneered the use of SPR spectroscopy for protein interaction analysis.

The SPR Navi™ 210 A instrument offers unique Modular Multi-Parametric Surface Plasmon Resonance (MP

-SPR) that gets your research beyond traditional SPR (single-parameter sensogram) measurements per-

formed by conventional instruments with focused beam, fixed

angle set-up like Biacore

offer.

How does this happen?

Well it’s a true multian-

gle goniometer (40~78

degrees) with multiwave-

length laser capability.

This means you can dis-

tinguish between bulk buffer effects and molecular binding

and see events outside the narrow angular range of traditional

focussed optics SPR.

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Formulaction:

Turbiscan

Sample stability

Founded by Gérard Meunier, Formulaction’s first product gave formulation chemists a tool, the MA1000, to

assess the stability of complex systems for the first time. They have since developed a complete range of

instruments from dedicated Heavy Oil testers to the general purpose Lab / Lab Expert to AGS with

temperature zones and automatic sample station. Turbiscan is used by over 1,400 labs in >40 countries,

because they can profile and quantify subtle changes in your emulsion and suspension and Turbiscan

shortens your testing times.

Turbiscan software (version 2.0) is now being released with a novel stability Index (TSI) to quantify,

compare and graph samples globally or in zones without complex user interactions.

Along with this innovation, Formulaction are

introducing a 6 sample instrument with a 4~80C

range and a compact foot print — the new

Turbiscan Tower also has an inbuilt LCD panel.

All Turbiscans use temperature to accelerate

changes. There is no centrifugal stress to alter

your materials natural structure or conflict with

bottle tests.

Formulaction:

Rheolaser

Microrheology

Formulaction’s Rheolaser utilises Diffusing Wave

Spectroscopy (DWS) for concentrated emulsions and

creams to characterise the microRheology of

materials.

As the Rheolaser doesn't use any external force, the

technique is “Passive microRheology” with no external

stress, so the measurement is made at rest. The only

force acting on the particles is due to native thermal

energy (Brownian Motion), and the response is

measured by probing the time-dependent Mean Square

Displacement of the particle (MSD).

In this, the displacement of the particles in a purely viscous

fluid grows linearly in time, whereas in an elastic fluid the

particles are limited in their displacement.

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Freeman Technology

FT4

Powder flow testing and Rheology

Freeman Technology's business is understanding powder flow behaviour and the design of

instrumentation for powder characterisation. The FT4 Powder Rheometer is a universal powder tester,

three instruments in one - a dynamic flow tester using patented technology, a shear cell tester and a

compression tester. FT4 comprehensively characterises all types of powders, and the available tests

reflect the complexity of powders in contrast to simple, single-number assessments of flowability.

This gives you essential information to improve the consistency and efficiency of your powder

processing.

Index Instruments

Refractive Index

Index Instruments have manufactured Scientific Instruments for over 30 years in their premises near

Cambridge. They specialise in Refractive Index technologies supplying the Confectionery, Food, Bever-

age, Pharmaceutical, Petrochemical, Essential Oils, Agriculture, Education and Sugar Industries.

Refractive Index as we know from Snell’s Law covers the bending of light as it passes between media; a

phenomena that is caused by a change in the speed of the light between the media.

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Lamy Rheology

Viscometry and Texture

Lamy Rheology with a long history in contract manufacture have been designing and man-

ufacturing their own range of viscometer products in their base near Lyon, France since

2006. Lamy distribute worldwide and their entry level viscometers are great value, the

novel “Black One” costs less than €2,500 (vat extra) complete with accessories.

The Low Shear LS400 uniquely measures low viscosities at low

shear rates and with small sample volumes. This uses a

COUETTE principle of rotating cup and fixed bob to measure

the Torque; the LS400 rotates at 0.1 to 100 rpm

and Torque goes from 0 to 0.006 mNm in 5 ranges.

A new product from Lamy is the affordable Tex’an

200 texture analyser shown at Pittcon and Achema.

This system allows measurement of “simple com-

pression”, TPA tests, BLOOM tests and TRACTION in

food, pharmaceutical and cosmetic industries.

Malvern:

Mastersizer 3000

Laser Diffraction Sizing

Malvern Instruments’ range of particle analysers has evolved to meet the needs of users in industry and

academia. Through continuous innovation with laser diffraction technology, Mastersizer has become the

gold standard particle size analyser. Mastersizer has always offered good software, reliable optics and

full validation support. Now we have a completely new Mastersizer with novel software, advanced engi-

neering; a totally new bench designed for the next decade! The all new Mastersizer 3000 analyser sizes

particles from 3.5 millimeter right down to 10 nanometer in the smallest of instrument footprints.

To complete the system completely new dispersion units offer simply the best in sample dispersion.

The Aero S dry powder dispersion accessory offers

choice of venturi and sample trays, air pressure and

feed rate, The dedicated air cell has

inlet air filters, is secure to fit in sec-

onds and very easy to clean. The

vacuum collector couples to the air

cell without any further manual in-

tervention!

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Particular Sciences Ltd

The Hydro MV and LV offer automatic liquid dispersion

for solvents and aqueous systems in medium volume and

large volume tanks respectively. These are completely

new designs that work with a new wet flow cell designed

to keep clean for longer. Both feature inbuilt flow path

sonication. The Hydro EV is an affordable, manual, dip-in

wet sample dispersion unit that can be used with

standard laboratory glassware. It also has flow path

sonication. The flow cell features a new window/seal design, easy to split and clean

in a quick fit cassette.

The Mastersizer 3000 software has a very wide range of facilities in a fresh layout

of records, graphs and tables that is easy to use and to tailor for your own needs.

Features like Data Quality, trend plots, result overlays and SOP player (that

effectively automates sequences of measurements) for method development all

come together to make this a powerful system for optimizing and validating

methods. You can even emulate MS2000 (and other systems) analyses in MS3000 software and evaluate

older designs using Lens Range emulation analyses.

Malvern

NanoSight

NTA technology

The NanoSight range of instruments utilizes Nanoparticle Tracking Analysis (NTA) to characterize particles

from 10nm -2000nm* in suspension. Each particle is individually but simultaneously analyzed by direct

observation and measurement of diffusion events. This particle-by-

particle methodology produces high resolution results for particle size

distribution and concentration, while visual validation provides users

with additional confidence in their data. Both particle size and concen-

tration are measured, while a fluorescence mode provides differentia-

tion of labelled or naturally fluorescing particles. Applications include

Exosomes, Nanotoxicology, drug delivery and viruses.

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Malvern:

Zetasizer Nano, mV and APS

Dynamic Light Scattering

The premium ranges of sub-micron instruments with the

highest sensitivity and widest range of measured

parameters and options available. This is the world’s most

popular system for the measurement of particle sizes from

0.6nm and molecular size from 980 Da using Dynamic

Light Scattering. Add to this zeta potential and

electrophoretic mobility using Laser Doppler

Microelectrophoresis, and molecular weight using Static

Light Scattering, and the Zetasizer Nano range is a

formidable system.

A new option for the Zetasizer range is the Solid Surface Cell that facilitates measuring the Zp of a surface or adsorbed material using tracer particles and stepping the measurement position incremen-

tally from the surface in a series of measurements—and extrapolating back to the real surface.

Also new is the tracer-particle

DWS Microrheology facility launched with the ZSP and

available as a retrofit for all

Zetasizer Nano ZS users. This

software is for studying vis-

coelastic properties of sam-

ples in dilute systems.

The Nano ZSP also features a completely new Protein meas- urement package for protein charge, protein mobility and

protein interactions.

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Malvern:

Morphologi

Vision and Chemical Imaging

The Malvern Morphologi G3 automated particle characterisation system is an

analytical tool that can provide high quality images AND statistically useful

particle shape and particle size measurements.

The G3 can analyze powders dry using its inbuilt dispersion system, or can

work with special slides in

holders (like the useful filter holders) to suit your

application. Wet dispersions and evaporated samples are

also catered for. A new development is a chemical

imaging variant the G3-ID that integrates automated

size/shape analysis of particles from 0.5 micron to 10

mm with chemical identification provided by Raman

microscopy.

Best in class particle morphological analysis by Malvern Instruments coupled with best in class Raman

spectroscopy by Kaiser Optical Systems Inc. means unparalleled performance, ease of use, and

commitment to customer satisfaction.

Malvern:

Viscotek

SEC & GPC with Intrinsic Viscosity and SEC MALS

Gel Permeation Chromatography/Size Exclusion Chromatography (GPC/SEC) is the technique of choice

for characterization of molecular weight and molecular structure of proteins, natural polymers and

synthetic polymers.

If you are looking for a complete GPC system or just an additional detector for your existing system we

can help. The Viscotek TDA sets the standard for multi-detector analysis with refractive index,

viscometer and light scattering detectors acting in concert, providing complementary data on the

macromolecules being analysed, and together offering Universal Calibration and Absolute Mol. Wt.

For BioPolymers and proteins SEC MALS is the standard technology and Viscotek now offer a 20 angle

true SEC MALS system for characterising samples, like IgG Molecular weight 147 kDa in this 3 peak

trace.

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Malvern:

Kinexus & Bohlin Rotational Rheology

Kinexus is a unique Rheometer designed for tomorrow's

rheology needs across all industries and application areas.

Designed by Malvern from the ground up, the Kinexus

rheology platform is the result of intensive product

development. Kinexus enables you to analyze the rheology

(flow/deformation properties) of your materials from liquids

to solids, from processability to product performance, from

temperature to time dependence and from simple viscosity

to complex viscoelastic parameters.

The Bohlin range of Gemini II rotational Rheometers are still available and fill many special niches and

applications, such as the Gemini HR Nano that offers nano-torque levels and enables users to probe

weak or sensitive material structures, yet retains a continuous torque range to 200mNm.The patented

Rotonetic 2 drive technology brings an unsurpassed range and sensitivity to control torque and speed

across all steady, dynamic and transient modes.

Malvern:

Rosand

Capillary Rheology

Rosand Capillary Rheometers simulate the high shear rate conditions of

plastic processing operations, such as extrusion molding.

In a Rosand system the heated sample is extruded through a die of known

dimensions and the shear pressure drop at set volumetric flow rates is

recorded. The basic output is a viscosity versus shear rate graph, but you

can also do extensional viscosity in twin barrel systems and many special

tests.

The bench top RH2000 that is suitable for most tests is shown at right.

Rosand also supply top of the range floor standing systems in strong H

frames for unsurpassed Rheometer performance in terms of speed

control, accuracy, and dynamic operating range.

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Malvern:

Parsum

Process size probe

Malvern's newest sensor is specifically designed to measure the

size and velocity of larger particles and granulates for chemical

and food industries. Parsum Real Time Sensor is a probe for

measuring particles with an average size of 50-6000µm and at

velocities from 0.01 to 50 m/s. The probe can be easily installed

directly into any gravity or pneumatic process line.

The Parsum probe simultaneously

measures particle size and velocity

of individual particles. In wet

granulation like this high shear wet granulation process, the Parsum was

able to precisely detect the

Granulation End Point and

even a late reduction of loose aggregates, all in a robust

package (see a real world installation photo).

Malvern:

Spraytec

Spray droplet sizing

Malvern Instruments’ Spraytec is a laser diffraction particle size

system specifically designed to address the unique requirements of

aerosol and spray droplet characterization across a wide range of

industries and applications. The Spraytec provides in-situ, real-time

droplet measurements in a fully validated package, giving accurate

and reproducible results, time and again.

The 10kHz sampling rate, 0.1~2000 micron size range and the wide range of accessories make Spraytec

an industry standard for continuous and intermittent spray studies.

Page 15

Malvern:

Insitec

Process sizing

Malvern Instruments’ laser diffraction technology is at the heart of the Insitec system. Its robustness

has allowed implementation of the Insitec sensor so that it copes easily with the rigours and demands

of an industrial process environment. The sensor's lenses allow the tuning of the instrument to the

needs of the process. The instrument is watertight and dustproof, and certified to industrial protection

rating IP66. It is CE badged and meets industrial grade electromagnetic compatibility (EMC) require-

ments for safe, reliable operation. ATEX versions, IS systems, polished surfaces and life cycle documen-

tation are all available.

Microfluidics

Particle Size Reduction

Microfluidics Corporation have a unique technology for particle size reduction

in a flowing system. Their HQ is Boston, Mass. and they have a base in

Lampertheim near Frankfurt with a team of specialists and engineers ready to

support customers worldwide.

Microfluidics’ high shear particle reduction technology is an ideal match with

our expertise in measuring Nano particles in suspension. Many customers

reduce size by milling or with classic homogeniser systems. This

offers a different approach, one that is scalable to process levels.

The LV1 system shown to the right is a complete package with

internal pumps for cell disruption at small scales. Its an ideal,

desktop system for those wanting to extract enzymes, DNA or

internal cell components.

The general purpose M110 shown below right works with external

gas pressure, can operate at higher flow rates and shears and is

scalable to the largest industrial systems. Their newest technology is

MRT, a system that reacts two fluid streams under pressure and

shear, to limit the size of any resulting crystals.

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Micromeritics:

Gemini

BET SSA

The Gemini systems have evolved from a microprocessor controlled, multi-

point Nitrogen BET SSA analyzer in 1990 to the latest compact BET system for

routine labs with isotherm needs.

Gemini runs with an empty reference tube alongside the standard sample

tube. This arrangement corrects for thermal issues and ensures fast, quality

data. Indeed Gemini is probably the N 2

BET of choice for low surface area

materials, such is the performance that comes from its unique design.

Now available with a standard or large volume Dewar, an optional dedicated

Po tube, choice of keypad control or real time PC operation, the Gemini is

more than a starter system. Users can tackle longer isotherms and avail of the larger volume of liquid

nitrogen and Po tube to ensure that Liquid N 2

stays above the sample, and that atmospheric pressure is

corrected for.

Micromeritics:

TriStar II and II Plus

BET SSA

The industry standard TriStar 3020 has 3 ports for simultaneous BET and gas adsorption isotherms. It

offers 21CFR Part 11 compliance and its performance in sensitivity, reproducibility, reliability and

throughput exceed all expectations. Standard features include unique Isothermal jackets, filler rods to

reduce free space and a selection of different tubes for samples. Tristar II is truly a workhorse for the

busier lab where surface area and mesotherm work is concerned.

The latest Tristar II has a small footprint, choice of vacuum pumps and a Kr option that extends the SSA

limit below 0.5 m2 of total surface in the tube, letting you work with materials with 0.1m2/gm SSA.

Tristar II Plus is a new version with corrosion resistant manifold, a new 40hr Dewar and all the latest

MicroActive software facilities embedded to make

reporting and analysis a breeze. For example this

integrated plot of BJH pore distribution extended with

Hg intrusion data is now possible.

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Micromeritics:

ASAP 2020HD

Physisorption system

The ASAP range since launch has become the definitive high end physisorption gas analyzer in the research

world. This is based on the numbers of literature citations for ASAP, and not just instrument installations.

Core to the ASAP’s design is the dual vacuum system with separate lines for sample degas and for analysis.

Oil-free “dry” vacuum option to prevent oil contamination and High Vacuum options for use with Krypton are

available. For Micropore work there are 1 micron transducers and in the

2020 HD (the High Definition version) there are 0.1 micron transducers

to go an order of magnitude lower before starting your isotherm – ideal

for MOF work. ASAP 2020HD has a range of other improvements

(including Hi-AC), all aimed at higher resolution and improved accuracy

in your isotherms.

In software ASAP has the complete package, including pioneering Non-

Local Density Functional Theory (NLDFT) and over 20 models available.

What else? Well, 12 gas inlet lines for maximum flexibility and the ability

to connect your output to a mass spectrometer.

Micromeritics:

ASAP 2050

Xtended Pressure Isotherms

The ASAP® 2050 Xtended Pressure Sorption Analyser is a capable of collecting high-resolution, high-

pressure adsorptive isotherms from vacuum to 10 atmospheres. While retaining many design elements

of the popular ASAP 2020, the ASAP 2050 offers an extended range of capabilities that enables the in-

strument to obtain data in an elevated-pressure environment. The instrument also allows the user to

collect traditional isotherms for determining surface area and porosity, but not in the ultra vacuum mi-

cropore regions.

 An optional chiller Dewar and recirculating bath allow the ASAP 2050 to be operated indefinitely - the instrument also supports the use of a standard Dewar with cryogen (typically liquid nitrogen or argon) that will provide at least 50 hours

of unattended analysis without refilling the Dewar

 Straight-walled, stainless-steel sample tubes are capable of safe operation up to 150 psi

 Rapid collection of non-monotonic isotherms with standard isotherm cycling software

 Special degas heating mantles can be used to prepare samples in situ on the analysis port prior to analysis

 Temperatures at each degas port, and the rate of temperature change, can be set and monitored individually from a few degrees above ambient to 450 C

 A user specified pressure setting protects the sample from steaming or dam- age during sample preparation

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Particular Sciences Ltd

Micromeritics:

3 Flex 3500

Multi sample High Resolution Micropore

The all-new 3Flex was engineered down to the smallest detail to improve sample throughput, stabi-

lize temperatures, reduce outgassing and most important increase the resolution and range of your

micropore isotherms. With three configurable analysis ports for high throughput 3Flex can operate

two or three micropore ports to meet current or future needs.

Standard mesopore, micropore, or physisorption ready instrument (Nitrogen or Krypton BET SSA), 5 gas ports



Pneumatically actuated, hard seal valves provide ultra- clean, leak-free operation



Stainless steel gas inlets, VCR fittings, and analysis manifold



Interactive Micro Active Software for data analysis with user- defined report options



Advanced instrument diagnostics



Small footprint conserves valuable lab space



Micromeritics: ASAP 2020 Chemi Chemisorption

Micromeritics offer several gas adsorption systems designed for catalysis research, for working with

reactive or corrosive gases and for chemical rather than physical assessment of surfaces.

The starting point is their Flowsorb systems with manual controls and TPD options shown right.

The ASAP range has a full 2020 Chemi package to work with

flowing gases over reactive samples, with temperature control,

inlets, gas switching, corrosion resistance, heated manifolds and

gas lines. Detectors are provided to allow analysis with

condensable vapours. Sample preparation occurs in situ to

prevent contamination prior to analysis. Samples can be

prepared at high temperatures (up to 1100 C) and at low

pressures (<10 -5 mmHg).

A benefit of using ASAP 2020 as your platform is the modularity

of the system. With the correct 2020 versions, it is easy to move

between BET, Isotherm, Micropore and Chemi work.

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Micromeritics:

Autochem II

Chemisorption

AutoChem II 2920 is an automated chemisorption analyzer that can provide the ability to conduct a

comprehensive array of precise studies of chemical adsorption and temperature-programmed reactions.

With this single instrument, you can acquire information about the physical properties of your catalyst,

catalyst support or other materials. It can determine percent of metal dispersion, active metal surface

area, acid strength, surface acidity, distribution of strength of active sites, BET surface area, and more.

AutoChem II safely performs pulse chemisorption, temperature-programmed reduction (TPR),

desorption (TPD), oxidation (TPO), and reaction analyses and does it

automatically. This unit is also available in a Corrosion Resistant version

AutoChem 2950 HP is a bench-top, microreactor system designed for

catalyst characterization up to 70 atmospheres ideal for researchers

who want to conduct experiments and characterize their materials at

conditions approaching commercial operation.

Micromeritics: AutoPore V new Mercury Porosimeter

Micromeritics' AutoPore V 9600 Series characterise a material’s porosity by applying various levels of

pressure on a sample immersed in mercury. The pressure required to intrude mercury into the sam-

ple’s pores is inversely proportional to the size of the pores. This is called Mercury Porosimetry, or

“mercury intrusion.”

The AutoPore V Series Mercury Porosimeters can determine a broader pore size distribution more

quickly and accurately than other methods. This instrument also features enhanced safety features and

offers new data reduction and

reporting choices that provide

more information about pore

geometry and the fluid

transport characteristics of

your material .

Easy to use penetrome-



ters,

Easy high pressure sam-



ple port loading,

MicroActive reporting



software

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Particular Sciences Ltd

Micromeritics:

Accupyc II

Helium Pycnometer

The AccuPyc II 1340 Helium Pycnometer is fast, fully automatic and facilitates sample volume and

density calculations for a wide variety of powders, solids, and slurries, with measuring sample volumes

from 0.01 to 350 cm 3 . The instrument performs most analyses in less than three minutes with

staggering accuracy. It is the gold standard in density testing. The standard AccuPyc II 1340 consists of

an integrated control/analysis module. For users who require higher

throughput, up to five additional analysis modules can be operated by

a single controlling unit. Naturally, each module has its own gas

connection and each module can contain a different size sample

chamber. Accupyc offers an

optional Peltier cooling

module of the cell

temperature for

demanding

samples and

applications.

Micromeritics: Geopyc

Envelope density

The GeoPyc 1360 Envelope Density Analyser measures the envelope density of porous objects of

irregular size and shape. Envelope density, or bulk density as it is sometimes called, is the mass of an

object divided by its volume where the volume includes that of its pore and small cavities. Envelope

density information is useful in characterizing catalysts, structural foams, insulators, ceramics, powder

metallurgy objects, and other manufactured goods larger than 2mm.

The GeoPyc follows a displacement technique that uses a quasi-fluid having a high degree of flowability

called DryFlo. The sample is placed in a bed

of DryFlo which is agitated and gently

consolidated about the sample. The GeoPyc

collects the displacement data, performs the

calculations, and displays and or prints the

results.

The unit can also report percentage porosity and specific pore

volume when a sample’s absolute density information (density

excluding pore and small cavity volume) is obtained from a Micromeritics AccuPyc helium pycnometer is

entered. This is especially useful for pharmaceutical roller compactor studies.

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Micromeritics:

MicroActive

Interactive software and reporting

Micromeritics’ innovative MicroActive software allows users to interactively evaluate isotherm data from Micromeritics ASAP, TriStar, and Gemini gas adsorption instruments (and all their *.smp files).

Users can easily include or exclude data, fitting the desired range of experimentally acquired data points using interactive, movable calculation bars. Isotherms can be viewed on either a linear or log scale and are available to the user under each calculation model. There is no need to generate reports to review results – see it graphically and interactively on screen.

The example shown here has bar limits for the calculation range between 0.05 and 0.3 P/Po selected. The sample was a high SSA material with excel- lent linearity...but you can see what restrict- ing the top end would do to the calculated BET. Easy, quick, reliable, advanced.

Micromeritics: Particulate Systems

Micromeritics offer a selection of OEM specialised instruments under this

brand, including the HPVA instrument designed to measure the high-

pressure adsorption isotherms with hydrogen, methane, carbon dioxide

and other gases using the static volumetric method. Typical applications

for this instrument include catalysts, zeolites, activated carbons, carbon

nanotubes, and hydrides. Understanding the adsorption characteristics

of materials is critical in the research and advancement of hydrogen

storage, fuel cells and batteries, stack gas scrubbers, and hydrocarbon

traps.

Pressure Ranges from ultra-high vacuum to 200 bars.



 Temperatures from cryogenic to 500 °C. Excellent control of sample temperature by means of a

constant temperature bath.

SPECTester Material Segregation Tester

The innovative SPECTester measures your sample with up to 6

unique components and, with a touch of the finger, reports the

pattern and the magnitude of sample material segregation.

Fully automated, it provides data about: component concentra-

tions, particle size differences, product uniformity, and up to 4

specific segregation mechanisms.

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Particular Sciences Ltd

Micromeritics:

Elzone II

Particle Counter

The new Elzone® II 5390 Particle Size Analyzer utilizes the electrical

sensing zone method to size samples without regard to optical

properties, densities, colors, and shapes. The Elzone quickly and

accurately determines the size, number, concentration, and mass of

a wide variety of organic and inorganic materials.

With automated routines for start-up, run and shut-down; blockage

detection and clearing, flushing/rinsing and calibration, the Elzone

determines particle size in a range suitable for a wide variety of

industrial, biological, and geological specimens. A high level of

accuracy and resolution, speed, ease-of-use, and compact

size make the Elzone equally suitable for industry, quality

control, and research and development laboratories .

Optical Activity

Polarimeters

Optical Activity are a leading manufacturer of digital Polarimeters for R&D and QC. They manufacture a

full range from routine, low cost units, through mid range systems to the highest specification

instruments available. Moreover they also provide a very wide range of sample tubes and certified,

traceable standards.

The range of high quality polarimeter sample tubes can be used in almost all polarimeter applications,

whether you need to measure the smallest amount of an expensive essential oil, or, if you have litres of

sample, one of our tubes is sure to be suitable.

The highest accuracy polarimeters are the PolAAr Series consisting of eight models - with options of

single wavelength, dual wavelength or multi

wavelength, a choice of two or three figure

accuracy and simple or full alphanumeric

keypads. All versions are full circle

polarimeters with a reading range of ± 90

angular degrees (in excess of ± 250 sugar

degrees) and can be 21 CFR Part II compliant

Page 23

Phenom World

Desk Top Electron Microscopy

To complement light microscopy and laser particle analysers, electron microscopy offers unrivalled

information on size, shape and surface characteristics. The Phenom Pure, for example is highly affordable

yet can produce quality images in minutes.

Featuring a simple sample loading system, easy to use

software and a B&W camera to “look around” the sample you

get from 20X to 20,000 X magnifications—ideal for most

powders and many materials you cant take down to a

dedicated EM unit.

Or you can move up to a

Phenom Pro and extend the

range up to 100,000X

magnification, a colour camera

for 20x to 120x ranges and

5kV or 10kV acceleration

voltages.

Postnova Analytics:

FFF

Asymmetric Field Flow Fractionation

Postnova Analytics are based in Landsberg west of Munich, Germany

and in Salt Lake City, Utah, USA where FFF was first developed by

Professor Giddings. They are simply the world leaders in Field Flow

Fractionation technology (FFF) and especially in Asymmetric Flow FFF.

This is an ideal technology for separating nano-particles and biotech

materials prior to analysis by DLS or SLS and complements Zetasizer

SEC in flow mode for those who

want a flexible and powerful

system to size eluting particles

and molecules.

FFF-LS technology is applied to separate and characterize

biopolymers, synthetic macromolecules, proteins, antibodies,

liposomes and nanoparticles for molar mass, particle size and

branching conformation.

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Particular Sciences Ltd

Relequa

Rapid moisture profiling of powders

Relequa is a unique analytical tool that provides information previously not readily available to the

pharmaceutical or food industry. Its method of moisture profiling analysis gives instant data about

moisture adsorption or evolution from pharmaceutical materials and products.

Designed and manufactured in Ireland, Relequa

uses the principle of Equilibrium Relative

Humidity (ERH) to produce data on moisture

problems. Measuring the profile gives

enormous insight into moisture impact on

pharmaceuticals, excipients and foods.

Sequoia Scientific

Field and submersible particle sizing instruments

Sequoia Scientific began operations in 1995 and are now based in Seattle (WA) in the USA.

Their mission is to develop scientific instruments for

research and measurements in aquatic environments. They

produce unique particle sizing instruments, not just splash

proof or watertight; but submersible in some cases down to

6000m.

The core product LISST-100x shown on the far right of the

photo is a rugged, submersible unit that can be left

underwater for months, passively collecting data on the size

of particles suspended in that environment. The size range is 1.25 ~ 250 or 2.5~500 microns, and the

data is transferred to PC and software analysis when recovered to the surface.

Variants like the LISST-LX unit can measure settling velocities in 8 size classes in situ. The

aerodynamically shaped LISST-SL is a self contained isokinetic sampling and sizing system for use in

flowing streams and rivers; again it operates unattended under water, you process the data on

subsequent retrieval..

The portable (yellow) box is a self contained, battery operated particle sizer for field use with solid

wastes or sediments or dirty water samples. The results are held in ASCI files for upload to PC and for

Excel reporting when you return to the Lab/Office.

The other (Perspex) box is a fixed location monitor to facilitate upstream/downstream waters where

you need to check on loads of contaminants or outfalls etc. Again it sizes the sediment loads for you

and holds the data.

Page 25

SMS:

Intrinsic

Water DVS

The development of Dynamic Vapour Sorption (DVS) by Professor Darryl Williams revolutionized vapour

sorption measurements in 1994. The manual desiccator test was brought into

the modern world of isotherms and computerized data capture and walk away

operation. All SMS models are designed, developed and produced in house.

The latest DVS models include a new, purpose designed SMS Ultra-Balance,

replacing dated Cahn technology.

The neat Intrinsic system shown right is the ideal instrument for routine use

in a QC lab or busy company.

Within R & D, applications range from studying polymorphism and stability to

studies of the bulk and surface adsorption effects of water and organic

vapors. It’s also a QC analysis technique for both scale-up and production,

and can be found measuring the efficacy and permeability of packaging materials, and the effects of

humidity and temperature on the samples within the packaging.

SMS:

Advantage

Water & solvent DVS

The DVS Advantage is the most advanced and versatile dynamic

gravimetric vapour sorption capabilities in the SMS range;

indeed it is the most complete system on the market.

Applications in food, pharmaceuticals, fibres, films and porous

materials are supported with extensive applications experience,

and include simple stability testing using water isotherms up to

sophisticated prediction of solid-solid interactions.

Sample pre-heating.



Organic vapours facilities



Active control of relative humidity and organic vapour.



Flexible sample geometry.



Options of video microscopy and NIR or Raman.



Typical 1 to 30mgm samples



Full vapour safety sensors & interlocks



Resolution from 0.05 ugm



21 CFR part 11 compliance



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Particular Sciences Ltd

SMS:

DVS - Vacuum

DVS

The new Dynamic DVS-Vacuum allows adsorption/sorption

experiments from atmospheric down to 10 -3 Torr.

The adsorption of vapours on porous materials is important

within numerous industries. Traditional gravimetric methods

are based on using a ‘static’ vacuum technique. This method is

limited by the fact that ‘out-gassing’ significantly contributes

to the measured pressure and hence sorption measurements.

You can now obtain accurate sorption properties of your

porous materials (with Solvents or Gases) using the latest DVS-

Vacuum analyzer.

 System can operate in static or dynamic vacuum modes for sorption and desorption via the use of both upstream and downstream pressure control from atmosphere down to 10-6 Torr.

 Ultimate requested pressure inside vacuum chamber is always maintained via our dynamic vacuum mode. This has the advantage of eliminating system out gassing issues at low pressures

Wide Temperature Range of 25 to 85 ºC



SMS:

Surface Energy Analyser

IGC

Unique to SMS is an instrument that uses pulses of solvent vapour

to probe the surface and bulk properties of particulate and

fibrous samples. Fine-tuning the probe molecules enables a

wealth of fundamental physico-chemical properties to be

elucidated including powder surface energies, acid/base/polar

functionality of surfaces, diffusion kinetics and solubility

parameters. The Surface Energy Analyser (SEA) offers an easy to

use package of this technology, commonly known as Inverse Gas

Chromatography (IGC) for Surface Energetics and Surface Energy

Heterogeneity Mapping.

o Unrivalled Accuracy

o Heats of Sorption

o Fully Automated

o Sorption Isotherms

o Humidity Control

o Phase Transitions

o Sample Preconditioning

o Diffusion Kinetics

o Wide Temperature Range

Page 27